When we talk about skin health and age defying treatments, the medical world has moved far beyond simply filling surface wrinkles or freezing facial expressions. Today, our patients come to our clinic with a very valid request. They say they do not want synthetic substances loaded from the outside; they just want their skin to repair itself. This is exactly where Rejuran, a polynucleotide treatment, steps in. It is truly one of the biggest biological breakthroughs of recent years and is completely changing the game in medical aesthetics.
On the Anatolian Side of Istanbul, right at our clinic in Kartal Bumerang Residence, we welcome patients who trust us from surrounding areas like Maltepe, Pendik, and Tuzla. Our core aesthetic philosophy for everyone is simple. We want you to defy time through true cellular restoration, without freezing your expression or losing your natural beauty. As a medical doctor with a background from the Gulhane Military Medical Academy, I strongly believe that every molecule applied to your skin must have a solid scientific foundation and the highest safety profile. In this guide, let us have a warm and transparent chat about what the Rejuran treatment really is, how it gives your skin its youth code back, and how we apply it safely in our clinic.
What is Rejuran? The Biological Architect of Your Skin
Rejuran is commonly known as Salmon DNA, but it actually goes way beyond a standard salmon DNA vaccine. It is a highly premium and patented polynucleotide formulation.
Polynucleotides are the basic building blocks of the DNA found in our cells. Rejuran is derived from the reproductive cells of wild salmon, which amazingly share a 98 percent biological compatibility with human DNA. But the real magic that sets Rejuran apart from ordinary products is its patented purification technology known as DNA Optimizing Technology. Because of this special process, the molecules are formed into long chains that are highly resistant to heat and tissue enzymes.
Think of it this way: Rejuran is not a dermal filler that artificially adds volume, nor is it like botox that stops your muscle movements. Instead, when it reaches the middle layer of your skin called the dermis, it acts as a biological messenger. It essentially gives a wake up call to your aged and sluggish cells, telling them to get back to work.
What Does Rejuran Do? The Real Effects of Cellular Repair
The reason we see Rejuran as a true youth elixir in our clinic is that it treats the overall fabric of your skin rather than just masking a single problem. Here are the wonderful things Rejuran does for your skin:
- Produces Your Own Collagen: By restarting the production of Type 1 collagen and elastin fibers which naturally decrease as we age, it tightens your skin and fills fine lines from the inside out.
- Deep Tissue Hydration: It incredibly boosts your skin water retention capacity. A few weeks after the procedure, our patients notice that famous natural glow that no topical cream can ever achieve.
- Barrier Repair and Thickening: Our skin gets thinner and more sensitive as we get older. Rejuran thickens the skin barrier and the dermal layer, making your skin much more resistant to environmental damage like sun and air pollution.
- Acne Scar and Pore Treatment: The Rejuran S series works wonders in leveling pitted acne scars and shrinking enlarged pores by maximizing your skin self healing capacity.
- Eye Area Rejuvenation: The most delicate skin on our face is right below our eyes. The specially formulated Rejuran I series is the most reliable non surgical method for treating dark circles, capillary pooling, and fine lines around the eyes.
How is the Rejuran Treatment Performed? A Step by Step Guide
The success of a medical aesthetic procedure depends on the product, but equally on the manual skill, anatomical knowledge, and surgical care of the physician. Here is how we perform the Rejuran application at Dr Mustafa Eray Erkek clinic:
1. Detailed Consultation and Facial Analysis Before we do anything, we carefully examine your skin age, loss of elasticity, and damage levels. We decide which Rejuran series is best for you and map out exactly which areas need the most attention.
2. Anesthesia for a Painless Experience Your comfort is essential to us. After cleaning the treatment area, we apply highly effective medical grade numbing creams. We wait about 20 to 30 minutes to make sure your skin is completely numb.
3. Micro Injection Technique We inject Rejuran into the middle layer of your skin using special mesotherapy needles that are as thin as a strand of hair. To make sure the medication stays and works in the tissue for a long time, we leave the product in tiny droplets, creating small bumps with tiny gaps between them. The whole thing takes about 15 to 20 minutes. You will not feel severe pain, just a very slight and tolerable stinging sensation.
4. Aftercare and the Disappearance of Bumps Right after the procedure, you will see tiny bumps on your face that look a bit like mosquito bites or small pearls. Please do not worry, this is the clearest medical proof that the medication was placed in the exact right layer. Because Rejuran is a dense molecule, it usually takes 24 to 48 hours for these tiny bumps to fully absorb and disappear into your skin.
Frequently Asked Questions
How many sessions will I need? Cellular repair is a journey that takes a little time. For lasting and visible results, I generally recommend 3 or 4 sessions spaced 2 to 4 weeks apart, depending on your age and skin quality. After that, a maintenance session once a year will help keep your skin looking youthful.
When will I start seeing results? You will not see instant changes like you do with synthetic fillers. About 7 to 10 days after your first session, you will start feeling more moisture and brightness. The real tightening and lifting effect begins around the fourth week as your cells produce new collagen, and it keeps getting better over the following months.
Does Rejuran cause allergies? It is incredibly safe. Salmon DNA is highly compatible with human DNA. Plus, thanks to the patented technology used during production, the product is completely purified from all proteins and substances that could cause an allergic reaction.
What should I pay attention to after the procedure? I always advise my patients not to wash their face for the first 24 hours. You should also avoid very hot environments like saunas or heavy sports and stay out of direct sunlight. Waiting at least 12 to 24 hours before applying makeup is also very important for your skin safety.
Rejuran Treatment Prices
One of the details our patients from Kartal, Maltepe, Pendik, and Tuzla wonder about the most is the price of a Rejuran session. Because of legal regulations in the medical sector and our ethical stance, we cannot share a standard price list online. However, I want you to know what determines the cost of this investment in your skin:
- Original Product Guarantee: Rejuran is one of the most premium polynucleotide products in the world. In our clinic, we only use 100 percent original Rejuran series approved by the Ministry of Health. We open the box right in front of you, ensuring the cold chain has been perfectly maintained. Cheap alternatives or black market products never enter our doors. This global quality standard is the main factor determining the price.
- Required Form and Quantity: The cost will depend on whether we are using Rejuran Healer for your entire face and neck, or just Rejuran Eye for your eye contour, and how many vials we actually need.
- Physician Expertise: The depth of the injection, the angle of the needle, and ensuring a smooth process reflect the surgical vision and experience of a specialist physician.
You really do not have to hide your skin fatigue, dehydration, and fine lines under heavy makeup. To remind your cells of their youth and defy the years without losing your natural beauty, I warmly invite you to our clinic at Kartal Bumerang Residence. To achieve the healthiest and most radiant version of your own skin, you can book a preliminary consultation to get a detailed skin analysis and create your personalized Rejuran treatment plan. The future of your skin is safe in scientific and reliable hands.





