When we look in the mirror, we eventually realize that the aging process is not just about fine lines on the surface. Especially from our late thirties onward, that tight, upward pointing V shaped youthful form of our face gradually begins to reverse. Due to the effect of gravity, decreasing collagen production, and weakening connective tissue, our cheeks begin to sag downward, our jawline becomes blurry, and our face takes on a tired, pulled down expression.
When our patients come to our clinic with these complaints, they usually carry a single concern. They say they want to lift the sagging in their face, but they are very afraid of their face swelling up like a balloon or taking on an artificial expression with fillers.
At our clinic located in Kartal Bumerang Residence, the center of the Anatolian Side of Istanbul, our medical aesthetic philosophy for our clients reaching us from the Maltepe, Pendik, and Tuzla regions is extremely clear. We want you to defy time without freezing your expression, without inflating your face, and by respecting your natural anatomy. With the surgical meticulousness and respect for tissue brought by the Gulhane Military Medical Academy tradition, we offer our patients one of the most innovative products in the medical aesthetic world that completely eliminates these fears: HarmonyCa. In this detailed medical guide, we transparently examine what this hybrid smart filler technology is that lifts the face upwards without inflating it with volume, what it does in our tissues, and how it is safely applied in a clinical setting.
What is HarmonyCa? The Hybrid Biostimulator of the Future
Until today, two different approaches generally dominated the medical aesthetics market. We either used standard Hyaluronic Acid fillers that give volume to the skin and fill hollows, or we preferred biostimulators that only trigger collagen production but do not yield instant results.
HarmonyCa, developed by the global medical aesthetics giant Allergan, is the first and most effective hybrid smart filler in the world that combines these two different powers in a single syringe. It contains two different medical agents working in perfect harmony with each other:
- Cross Linked Hyaluronic Acid: It ensures that the skin is instantly moisturized, supported, and the face is mechanically lifted the very minute the procedure is performed.
- Calcium Hydroxylapatite Microspheres: This is a biocompatible mineral naturally found in human bone and tooth structure. When these microspheres settle deep into the skin, they stimulate the fibroblast cells, which are the load bearing columns of the face, allowing them to weave a brand new and strong collagen network.
HarmonyCa is not an inflating material, it is a structuring and stretching material.
What Does HarmonyCa Do? Dual Stage Rejuvenation
The biggest reason why HarmonyCa is preferred when treating accumulations and sagging on the face is the dual time miracle it creates in the tissue. When injected into your skin, it provides the following biological and aesthetic benefits:
- Instant Lifting Effect: Right after the procedure, when you look in the mirror, you see that the sagging in your cheeks has instantly recovered and your face is standing upright outward thanks to the power of the hyaluronic acid it contains. This provides an instant satisfaction for our patients.
- Lasting Collagen Construction: The real cellular magic begins weeks later. Calcium hydroxylapatite particles build an invisible scaffold under the skin. Your body clings to this scaffold and bursts into Type 1 and Type 3 collagen synthesis. As months pass, the fabric of your skin tightens, pores shrink, and the looseness in the skin becomes taut like a corset sewn from the inside.
- Restoring the Facial Oval: Because it is applied to the outer edges of the face, it makes the jawline prominent and erases that fallen expression under the cheekbones.
- Eliminating the Pillow Face Risk: Fillers containing only hyaluronic acid widen the face and make the patient look heavier or bloated when used in high amounts to recover sagging cheeks. HarmonyCa does not widen the face horizontally; it mechanically narrows the tissue and pulls it up.
How is the HarmonyCa Treatment Performed?
The HarmonyCa application is not a simple filler injection, it is a medical intervention called a Liquid Face Lift that requires a high level of anatomical knowledge. At the clinic of Dr Mustafa Eray Erkek, this procedure is performed with strict adherence to surgical principles and patient safety protocols through the following steps:
1. Vectoral Analysis and Planning Before the procedure, your facial connective tissue, muscle structure, and sagging vectors are examined millimeter by millimeter. HarmonyCa is not applied to the center of the face like the under eye or lip edge. A plan is made for the outer frame of the face, which we call the C line, targeting the outer contour of the cheekbone, front of the ear, and jaw corner. We mark exactly from which points the tissue will be hung upwards.
2. Anesthesia for Maximum Comfort Numbness is achieved by applying local anesthetic creams to the procedure area. At the same time, the HarmonyCa formula itself contains lidocaine, a numbing agent. This way, the procedure process passes extremely comfortably and painlessly for our patients.
3. Safe Injection with a Cannula Our biggest surgical difference in this treatment is that we use blunt tipped cannulas instead of sharp needles. A cannula is a flexible medical tube with a blunt tip that advances under the skin without cutting veins or nerves, gently pushing them aside. By opening only a single entry hole, the entire outer frame of the face is reached in a fan shape. Thanks to the use of a cannula, the risk of bruising, intravascular occlusion, and tissue trauma drops to almost zero.
4. Post Procedure Massage and Shaping After the product is placed in the deep subdermal plane under the skin, a special medical massage is applied to ensure a homogeneous distribution and to lock the tissue upwards. Following this process, which takes about 30 to 40 minutes, the patient can directly return to their social life.
Frequently Asked Questions
How permanent are the results of the treatment? Thanks to the dual acting structure of HarmonyCa, its permanence is much longer than standard fillers. Even though hyaluronic acid is absorbed by the body over time, your own collagen skeleton created by calcium hydroxylapatite is permanent. The duration of the effect can last an average of 18 to 24 months depending on the metabolism and lifestyle of the patient.
Will I have bruising or excessive swelling on my face after the procedure? Because we use cannula technology, the possibility of bruising is very low. For the first few days, there may be very slight edema or vague sensitivity at the entry points depending on the water retention capacity of the medication and tissue reaction. However, this is not a swelling that will keep you away from your social or work life.
What should be considered after the procedure? We recommend that you avoid strenuous exercises, excessively hot environments like Turkish baths or saunas, alcohol consumption, and sleeping face down during the first 24 hours following the application. For makeup, it is generally safer medically to wait until the day after the procedure.
Is HarmonyCa suitable for everyone? Who should not get it? It is ideal for almost any patient over the age of 30 who complains of sagging, loss of elasticity, and looseness in the face and who does not want a surgical operation. However, this procedure is not medically applied to pregnant women, breastfeeding mothers, those with active autoimmune diseases, and individuals with a previously known allergy to the components of the medication.
How Are HarmonyCa Prices Determined?
One of the issues our patients coming from the Kartal, Pendik, Tuzla, and Maltepe regions are most curious about when planning their budget is the pricing of HarmonyCa. Due to medical ethics, Ministry of Health rules, and the fact that every patient facial anatomy is as different as a fingerprint, it is not legal or correct for us to share a standard price on the internet. However, in accordance with our principle of transparency, the criteria determining the prices are as follows:
- Amount of Product Needed: Depending on the degree of sagging in the face, the amount of product to be placed on both cheeks varies. While 1 box of HarmonyCa consisting of 2 syringes in a session is generally sufficient, more syringe usage may be required to fully hang the outer frame of the face in patients experiencing advanced tissue loss. The cost of the treatment is shaped entirely according to the number of sterile tubes to be used for you.
- Global Quality Standard: There are many different fillers on the market, but HarmonyCa is a patented Allergan product that has passed FDA approval processes with years of clinical studies behind it. In our clinic, no product that could harm you, has a broken cold chain, or is counterfeit is ever used. This 100 percent original product guarantee lies at the foundation of the pricing.
- Where Surgery Meets Art: This product is of no use when applied to the wrong area of the face. The amount you pay is not just the cost of a syringe; it is the price of buying the safety and expertise of a physician who knows the vein and nerve networks in your face by heart, who was raised with Gulhane Military Medical Academy discipline, and who uses the cannula technique safely.
You do not have to lose the meaning of your face, your mimics, and that characteristic expression of yours while resisting gravity. We welcome you to our clinic in Kartal Bumerang Residence to tighten your sagging tissues from the inside like a shield and present your skin with a brand new collagen network. You can get a free preliminary consultation appointment to discuss your completely personalized Non Surgical Face Lift plan and meet this unique harmony that biotechnology will offer to your skin. Your health and beauty are under guarantee in professional hands.





