The passage of time, environmental factors, stress, and the damaging effects of the sun gradually deplete the natural building blocks of our skin. With the decrease of collagen and elastin fibers beneath the skin, dullness, fine wrinkles, dehydration, and a loss of elasticity (sagging) begin to appear on our faces. Although most of our patients turn to procedures that provide instant volume to erase this tired look, any aesthetic intervention performed without repairing the skin’s “fabric”—its cellular quality—will remain incomplete.
Exactly at this point, the Salmon DNA treatment, one of the most powerful weapons modern medical aesthetics offers for cellular renewal, comes into play. On the Anatolian Side of Istanbul; in our clinic at Kartal Bumerang Residence, we approach skin health with a “holistic and restorative” perspective, especially for our clients reaching us from the Maltepe, Pendik, and Tuzla regions. With our analytical, meticulous, and patient-safety-centered vision brought by the Gülhane Military Medical Academy (GATA) tradition, our core motto is this: “Defy time without freezing your expression or spoiling your naturalness.” In this comprehensive guide, we transparently examine all the medical details of Salmon DNA, which virtually reloads the code of youth into your skin, and its worldwide gold standard, the Rejuran treatment, under the principles of Dr. Mustafa Eray Erkek.
What is Salmon DNA (Polynucleotide) Treatment?
Salmon DNA treatment, as the name suggests, is the process of administering “polynucleotide” chains—obtained from salmon sperm using high technology and showing a 98% similarity to human DNA—into the skin via micro-injection.
This procedure is not a standard moisture vaccine or a dermal filler. It does not provide artificial volume or a synthetic substance to the body from the outside. When polynucleotides reach the middle layer of the skin (dermis), they act almost like a “master builder.” By stimulating the fibroblast cells that give the skin its flexibility and youth, they maximize the body’s own natural collagen and hyaluronic acid production. Salmon DNA increases the skin’s diminishing water retention capacity, repairs the cellular damage caused by free radicals, and rejuvenates the tissue with its own biology.
What is Rejuran? The Gold Standard in Salmon DNA Treatment
In the world of medical aesthetics, not every Salmon DNA product has the same effect and purity. In our clinic, per our medical principles, we always prefer evidence-based and top-tier biotechnological products. In this field, one of the undisputed most premium and purest polynucleotide formulations in the world is the Rejuran (Rejuran Healer) series.
Rejuran consists of long-chain polynucleotides produced with the patented DOT (DNA Optimizing Technology). Compared to ordinary Salmon DNA vaccines, it stays in the tissue much longer, and its cellular repair capacity is significantly higher. In smoothing fine wrinkles, treating scars, and especially rejuvenating highly sensitive areas like the under-eyes, Rejuran creates extraordinary and completely natural results when applied under a doctor’s supervision.
What Problems Does Salmon DNA (Rejuran) Treat?
This biological restoration, which triggers the skin’s self-healing mechanism, has a wide range of uses:
- Dull and Dehydrated Skin: By massively increasing the skin’s water retention capacity, it restores that famous natural “glow” coming from within.
- Fine Wrinkles and Loss of Elasticity: It repairs aging signs on the face, neck, décolleté, and hands at the cellular level by increasing collagen production.
- Acne Scars and Blemishes: Thanks to its ability to repair damaged tissue (tissue regeneration), it helps level out pits and scars.
- Under-Eye Dark Circles and Lines: It thickens the under-eye area, which has the thinnest skin on our face, and alleviates dark circles and fine lines by regulating capillary circulation (The Rejuran I series is specifically designed for this area).
Frequently Asked Questions About Salmon DNA Treatment
Honestly addressing the question marks in the minds of the patients who apply to our clinic is as important as the success of the treatment. Here are the most frequently asked questions:
1. Is the Salmon DNA / Rejuran application a painful procedure? Patient comfort is our primary priority. Before the procedure, highly effective local anesthetic creams are applied to your skin, and the area is expected to become completely numb. Since the application is performed with “mesotherapy needles” that are even thinner than a strand of hair, usually only a slight mosquito bite or tingling sensation is felt. It is a highly comfortable medical procedure.
2. Will there be bruising or bumps on my face after the procedure? After the application, the formation of tiny bumps (papules) resembling mosquito bites and slight redness at the injection points is an indicator that the medication has been administered to the correct layer. Due to Rejuran’s dense structure, these bumps completely spread under the skin and disappear within a few days. Since cannula or micro-needling techniques are used, the risk of bruising is quite low; even if it occurs, it passes within a few days.
3. Does Salmon DNA cause allergies? Our patients with fish allergies are usually concerned about this. However, top-tier polynucleotide products like Rejuran, despite being derived from salmon, are completely purified from proteins and allergens using advanced technology. Therefore, the risk of causing an allergic reaction in the human body is almost non-existent; nevertheless, your detailed medical history is strictly evaluated during our clinical preliminary consultation.
4. How many sessions does the treatment take, and when will I see the results? Because we initiate a repair at the cellular level, the results do not appear instantly like a filler procedure. Your skin needs time to produce collagen. Visible brightening and revitalization usually begin 1-2 weeks after the first session. For lasting and cellular improvement, applying 3 or 4 sessions at intervals of 2 to 4 weeks, on average, depending on your skin age and problem, is recommended.
5. Does Salmon DNA replace Botox or Filler procedures? No, these procedures are not alternatives to each other, but perfect complements. Botox smooths mimic wrinkles; fillers replace lost volume. Salmon DNA (Rejuran), on the other hand, repairs the “quality and fabric” of the skin. Without a healthy, smooth, and moisturized skin fabric, no filler or Botox can truly showcase itself in an elegant way.
6. Who cannot have Salmon DNA applied? It is not applied to pregnant and breastfeeding mothers as there are no clinical studies on them. Additionally, per our medical protocols, this procedure is not performed on those with active infections (herpes, inflamed acne) in the application area, individuals with uncontrolled autoimmune diseases, and those with blood clotting disorders.
Salmon DNA (Rejuran) Prices: Quality and Expertise Criteria
One of the most frequently asked questions by our patients reaching our clinic from the Kartal, Maltepe, Pendik, and Tuzla regions to receive aesthetic consultancy is the session prices. In accordance with our medical ethical rules and legal regulations in the field of medical aesthetics, it is not appropriate to share a clear price or package figure on the web. However, knowing how Salmon DNA treatment costs are shaped allows you to make the rightest investment for your health:
- Brand and Biotechnological Class of the Product Used: The biggest factor determining the price is the quality of the product to be injected into your skin. Naturally, the prices of a standard, cheap Salmon DNA vial and the patented, high-cost Rejuran Healer series with proven cell renewal capacity are different from each other. In our clinic, no product whose reliability and efficacy have not been approved by authorities like the FDA/CE is used.
- Required Number of Sessions: The repair process needed for the moisture requirement of a patient in their late 20s and the elasticity loss of a patient in their 50s is not the same. The total cost of the treatment is shaped by the number of sessions to be determined by your doctor.
- Medical Experience of the Physician: Injections made into the middle layer of the skin (dermis) require serious anatomical knowledge. Administering the product to the correct depth, at the correct angle, and in the appropriate dose directly affects the success of the result to be achieved. This procedure is not simple cosmetic care but a medical intervention requiring GATA discipline and surgical meticulousness.
If you too wish to regain the natural glow, firmness, and health that your skin has lost, completely with your own cellular biology and far from synthetic appearances; we would be pleased to welcome you at our clinic in Kartal Bumerang Residence. In our center, which you can easily reach from Maltepe, Pendik, Tuzla, and all surrounding districts, you can book a preliminary consultation appointment to analyze your skin’s true needs and create your personalized treatment plan. Your health and naturalness are safe in expert hands.
